• ICH induced striatal lesion produced

  2022-01-04

  

  ICH-induced striatal lesion produced a reduction of EAAT1 expression analogous to the decreased glutamate uptake at 6 h. The combined reduction of excitatory amino mct inhibitor transporters and of glutamate uptake activity might explain the well-known glutamate excitotoxicity following brain ische

• Phylogenetic trees of receptors for peptides similar to gluc

  2022-01-04

  

  Phylogenetic trees of receptors for peptides similar to glucagon from diverse vertebrate species typically are similar to the tree presented in Fig. 3 (Sivarajah et al., 2001, Chow et al., 2004, Irwin and Wong, 2005, Cardoso et al., 2005, Cardoso et al., 2006, Ng et al., 2010, Park et al., 2013, Hwa

• The caseins are a family

  2022-01-04

  

  The caseins are a family of milk phosphoproteins whose biological function is to provide supersaturating concentrations of calcium, phosphates, and essential Retigabine dihydrochloride to the neonate (Vonderhaar and Ziska, 1989). α- and β-caseins, the most abundant of the milk caseins, are describe

• GHSR A s have high levels of constitutive activity

  2022-01-04

  

  GHSR-1A's have high levels of constitutive activity and recent investigations show that constitutively active GHSR-1As in the absence of ligand (ghrelin) binding can have effects on feeding and energy balance (Mear et al., 2013, Petersen et al., 2009). Furthermore, GHSR-1As are capable of dimerizing

• br Acknowledgements This work was supported by

  2022-01-04

  

  Acknowledgements This work was supported by grants of the Argentine National Research Council (CONICET, PIP 0662). The authors express their appreciation to the Transmission Electron Microscopy Service (MET) of the Faculty of Veterinary Medicine of the National University of La Plata (Argentina)

• BI6727 Macroautophagy hereafter referred to as autophagy dep

  2022-01-04

  

  Macroautophagy (hereafter referred to as autophagy) depends on an intracellular lysosome-dependent degradation system that maintains cellular metabolism and homeostasis [11]. Genes involved in these processes are termed autophagy-related genes (ATGs), which regulate autophagosome formation and compl

• Our present data together with other studies have shown

  2022-01-04

  

  Our present data together with other studies have shown that the communication of stroma and cancer cells via ECM-cell interaction led to the primary activation of FAK [41]. Here we propose a model depicting an important role of ADAM12-L in the regulation of ESCC invasion and metastasis. ADAM12-L ov

• br Introduction br Results br Discussion br

  2022-01-04

  

  Introduction Results Discussion Experimental Acknowledgment Introduction Endocannabinoids, N-arachidonoylethanolamine (AEA) and 2-arachidonoylglycerol (2-AG) have been found in most mammalian tissues and they stimulate cannabinoid CB1 and CB2 receptor activity thereby modulating se

• Macrophage populations are prominent in active IBD Strober a

  2022-01-04

  

  Macrophage populations are prominent in active IBD (Strober and James, 1986) as compared to healthy donors. Further, percentages of macrophages are increased in DSS-induced colitis (Grose et al., 2001, Ogawa et al., 2004). IBD is also linked to an influx of neutrophils and depletion of neutrophils b

• br Conclusions br Acknowledgement br Introduction The macrop

  2022-01-03

  

  Conclusions Acknowledgement Introduction The macrophage is an important cell species that plays key roles in innate immune responses and inflammatory reactions through phagocytosis of foreign bodies and secretion of inflammatory mediators such as interleukin (IL)-1, tumor necrosis factor (T

• Finally LC ESI MS MS was applied to explore

  2022-01-03

  

  Finally, LC-ESI-MS/MS was applied to explore the effects of increased fT4 levels 4 and 8 weeks after induced thyrotoxicosis and have revealed an upregulation of proteins involved in blood coagulation, thus providing a clear association [126]. Conclusions Introduction Diabetes mellitus (DM) ha

• The action of niacin in upregulating cAMP is most

  2022-01-03

  

  The action of niacin in upregulating cAMP is most likely determined by the milieu of adenylyl cyclase isoforms expressed in macrophages that are responsive to GPR109A activation. Several adenylyl cyclase isoforms, namely AC2, AC4 and AC7, are responsive to the stimulatory action of Gβγ G-protein sub

• Even though for almost years GnRH was

  2022-01-03

  

  Even though for almost 30 years GnRH was considered the main neuropeptide regulating gonadotropin release in vertebrates, Tsutsui et al. (2000) discovered, in the Japanese quail, Coturnix japonica, a hypothalamic neuropeptide that directly inhibits gonadotropin release, and thus named as gonadotropi

• br Investigations br Genetics GLUT is a membrane bound

  2022-01-03

  

  Investigations Genetics GLUT1 is a membrane-bound glycoprotein that provides base-rate glucose transport across blood-tissue barriers. It is constituitively expressed in erythrocytes, learn more microvessels and astroglia. The gene exclusively associated with GLUT1 is SLC2A1, located on chrom

• After the origin of the family

  2022-01-03

  

  After the origin of the family of genes for receptors for peptides similar to glucagon, the genes have not remained static. Not only have their sequences evolved, but also like peptides similar to glucagon (Irwin, 2001, Irwin, 2009, Irwin, 2012, Ng et al., 2010, Hwang et al., 2013), the numbers of g

15753 records 498/1051 page Previous Next First page 上5页 496497498499500 下5页 Last page