• The creation and maintenance of

  2018-11-08

  

  The creation and maintenance of subcutaneous patient-derived xenografts (PDX) from fresh or cryopreserved ACC tissue (Moskaluk et al., 2011) provided a renewable source of ACC casr for validation of our CSC hypothesis. As we previously demonstrated, these PDX models reproduced ACC morphology and ma

• Multi electrode array approaches have been proposed as a too

  2018-11-08

  

  Multi-electrode array approaches have been proposed as a tool for detecting functional changes in electrically excitable cells, including neurons, exposed to drugs or toxins and allow use in high throughput studies (McConnell et al., 2012). Although there are a number of electrophysiological measure

• Collectively these results indicate that both CXCR and CXCR

  2018-11-08

  

  Collectively, these results indicate that both CXCR4 and CXCR7 are necessary for proper differentiation and function of hiPSC-CMs and hECTs, but they might act by separate mechanisms. There have been multiple reports suggesting differential signaling and activity of SDF-1/CXCR4 and SDF-1/CXCR7 pathw

• Genome wide association studies GWASs represent another unbi

  2018-11-08

  

  Genome-wide association studies (GWASs) represent another unbiased approach that has proven particularly successful in humans for gene discovery of numerous disease phenotypes (Hindorff et al., 2015). Encouraged by this success, GWASs also have been proposed in mice using a recently developed panel

• Our study showed that neurite length and

  2018-11-08

  

  Our study showed that neurite length and the ratio of apoptotic luliconazole in FALS- and FUSH517D/H517D iPSC-derived neurons were the same as in control motor neurons. With several stresses especially in glutamate treatment, however, FALS- and FUSH517D/H517D HB9-positive motor neurons exhibited sh

• br Results br Discussion Similarly to unconditioned adult

  2018-11-08

  

  Results Discussion Similarly to unconditioned adult recipients, transplantation of allogeneic HSC into non-ablated fetal hosts faces serious challenges. Immunologic barriers posed by the mother\'s immune system (Merianos et al., 2009; Nijagal et al., 2011) and by the emerging innate and adapti

• br Experimental Procedures br Author Contributions br Acknow

  2018-11-08

  

  Experimental Procedures Author Contributions Acknowledgments We thank Ms. Y. Ogata for technical assistance. Financial support for this research was provided by the Uehara Memorial Foundation, Takeda Science Foundation, the Naito Foundation, the Ministry of Education, Culture, Sports, Scien

• In the present study we carried out an expression

  2018-11-07

  

  In the present study, we carried out an expression profile analysis of GPCRs in mESCs and mESC-derived ECs, and observed inordinately high expression of the orphan receptor GPR56 (Huang et al., 2008) and, importantly, of PAR1 in the ECs generated from ESCs. We focused on PAR1 not only as it is highl

• Accumulating evidence documents racial disparities in

  2018-11-07

  

  Accumulating evidence documents racial disparities in allostatic load, such that blacks report significantly higher levels of allostatic load than whites (Crimmins & Saito, 2000; Geronimus et al., 2006; Kaestner, Pearson, Keene, & Geronimus, 2009; Peek et al., 2010; Seeman, Epel, Gruenewald, Karlama

• The predominance of psychosocial theory including depletion

  2018-11-07

  

  The predominance of psychosocial theory including depletion of psychosocial assets such as social capital and social support theory in oral health literature is mirrored in its use in research in general health literature (Islam, Gerdtham, Gullberg, Lindstrom & Merlo, 2008; Murayama, Fujiwara & Kawa

• br Hydrogen production by chemical

  2018-11-07

  

  Hydrogen production by chemical looping reforming of SWCO Results and discussion Conclusions The main conclusions that can be drawn from the present study are the following: Introduction As reported by Coetzee et al. (2007) HG-9-91-01 mine drainage (AMD) occurs in sulphide-bearing mine

• At a later point of time when

  2018-11-07

  

  At a later point of time, when the fastest arriving stimulus used in a previous associative learning event reaches the nervous system, it reactivates the IPL and activates the inter-LINKed postsynaptic terminal from a lateral direction (Fig. 1D). When the postsynaptic terminal is in a background sta

• br Conflict of interest statement br Author contributions

  2018-11-07

  

  Conflict of interest statement Author contributions The following are the supplementary data related to this order A-366 article Acknowledgements We thank the NIAID Tetramer Facility (Emory University, Atlanta, GA) for supplying CD1d tetramer and Dr. T. Camou (National Reference Laboratory

• Progress toward the treatment of three major parasitic

  2018-11-07

  

  Progress toward the treatment of three major parasitic diseases (sleeping sickness, Chagas disease, and leishmaniasis) was recently demonstrated in an article published online last month in the journal (August 8, 2016). Collectively, these three diseases affect 20 million people per year, resulting

• The extreme genetic diversity between HIV subtypes has pheno

  2018-11-07

  

  The extreme genetic diazoxide between HIV-1 subtypes has phenotypic consequences in vitro including differential HIV-1 mRNA transcriptional control (Montano et al., 2000; van et al., 2004), protease activity (Velazquez-Campoy et al., 2001), integration site selection (Demeulemeester et al., 2014),

15446 records 1012/1030 page Previous Next First page 上5页 10111012101310141015 下5页 Last page