Alternative approaches to LV are non viral vectors

2018-10-20

Alternative approaches to LV are non-viral vectors such as RNA or DNA, which are considered safer due to their integration-free nature (Hardee et al., 2017). However, manufacturing RNA is expensive and difficult because RNA has a propensity to degrade (Yin et al., 2014). On the other hand, DNA plasm

Adrucil The approach for stem cell identification utilized h

2018-10-20

The approach for stem cell identification utilized herein is functional, based on the relative quiescence and thus label retention property of stem Adrucil within a mixed epithelial population. Long-term 5-bromo-2′-deoxyuridine (BrdU) retention has been previously used to label stem cells in vivo a

Introduction The pluripotency promoting role of the reprogra

2018-10-20

Introduction The pluripotency-promoting role of the reprogramming factors OCT4, SOX2, KLF4, and MYC (OSKM) is widely appreciated. However, these reprogramming factors also promote expression of non-pluripotency genes. For example, OCT4 (Pou5f1) directly promotes expression of genes important for mo

These data are in agreement with prior studies demonstrating

2018-10-20

These data are in agreement with prior studies demonstrating that hyaluronan levels play a critical role in determining the site of HSC lodgment/engraftment following transplantation (Avigdor et al., 2004; Ellis et al., 2007, 2009, 2011; Nilsson et al., 2003), and that HSC exhibit preferential engra

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2018-07-29